Molecule activation with s-block and p-block combinations

Aromatic, highly stable, benzene can be activated according to a Frustrated-Lewis-Pair concept. Combined action of a “naked” Ca2+ cation and nucleophilic Al(I) leads to dearomatization.

Angew. Chem., Int. Ed. 2018, 57, 14169
Facile Benzene Reduction by a Ca2+​/Al(I) Lewis Acid​/Base Combination
DOI: Angew. Chem. Int. Ed.10.1002/anie.201809236

Angew. Chem., Int. Ed. 2019, 58, 15496
Calcium-​Catalyzed Arene C-​H Bond Activation by Low-​Valent Al(I)
Angew. Chem. Int. Ed. 10.1002/anie.201908978